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Recent Grant and Contract Support at CHDS (partial list)*

Project Title: Immune Markers in Pregnancy and Breast Cancer
Description: Examines clinically observed indicators of placental function as prospective predictors of maternal breast cancer.
Funding Source:
National Cancer Institute

http://www.cancer.gov/

http://jncicancerspectrum.oupjournals.org/cgi/content/full/jnci;93/15/1133

Project Title: Prenatal Organochlorine Exposure and Human Reproduction
Description: Pilot study to collect semen samples from CHDS sons as preparation for a proposal to fund an examination of the relationship between prenatal exposure to organochlorines and semen quality.
Funding Source:
National Institute of Environmental Health Sciences

http://www.niehs.nih.gov/

http://aje.oupjournals.org/cgi/content/abstract/155/7/664

Project Title: Breast Cancer and Organochlorines
Description: Considers timing of exposure in a prospective epidemiological study of the relationship between DDT exposure and breast cancer.
Funding Source:
National Cancer Institute

http://www.cancer.gov/

http://www.webstracts.com/ISEA2002/catsort/10148.pdf (8k PDF File*)

* Adobe Acrobat Reader is required to view this document.


Project Title: Prenatal Exposure to Organochlorines and Fecundability
Description: A prospective study to investigate the relation between prenatal exposure to environmental chemicals and fecundability (time to pregnancy) in adult CHDS daughters.
Funding Source:
National Institute of Environmental Health Sciences

http://www.niehs.nih.gov/

http://www.niehs.nih.gov/dert/profiles/hilites/2003/ddt-dde.htm

Project Title: The Epidemiology of Growth Factors and Immune Function in Pregnancy: Relation to Maternal Breast Cancer
Description: Investigates the relation between prospectively obtained measures of serum markers of placental function in pregnancy and breast cancer.
Funding Source:
Department of Defense, U.S. Army Breast Cancer Research Program

http://cdmrp.army.mil/bcrp/

http://cdmrp.army.mil/bcrp/era/abstracts2002/p13_chemoprevention/p13_combined.pdf (172k PDF File*)

* Adobe Acrobat Reader is required to view this document.


Project Title: Prostate Cancer: Prospective Serum Markers in Blacks and Whites
Description: Examines the possible relationship of genetics and serum levels of androgens and growth factors to the risk of prostate cancer in African-American and Caucasian men.
Funding Source:
California Cancer Research Program

http://www.crponline.org/

Project Title: Maintenance of the Child Health & Development Studies
Description: Supports the basic maintenance of data files, provides for the sharing of public use files for other investigators, and gathers new information about study participants as it becomes available.
Funding Source:
National Institute of Child Health and Human Development

http://www.nichd.nih.gov/

Project Title: Pregnancy Hormones, Environment, Genes & Offspring Health
Description: This planning grant tests the feasibility of creating a genetic library for the CHDS that can be used to understand how genes interact with environment to influence health of parents and offspring. It includes intensive examination of the ethics of genetic studies in long-term studies.
Funding Source:
National Institute of Environmental Health Sciences

http://www.niehs.nih.gov/

Project Title: Can Placenta Factors Explain Race Patterns of Breast Cancer?
Description: Higher birth weights have been reported to increase breast cancer risk, and birth weights of mothers and daughters are highly correlated. However, race/ethnicity patterns for birth weight (lowest for African Americans and Asians, higher for Hispanics and non-Hispanic whites) do not match patterns of breast cancer in California (lowest in Asians and Hispanics). A key to progress in breast cancer prevention will lie in reconciling critical paradoxes like this one. This grant examines whether race differences in placental characteristics shed light on this paradox.
Funding Source:
California Breast Cancer Research Program

http://www.cbcrp.org/research/PageGrant.asp?grant_id=2276

Project Title: Early Determinants of Adult Health --Starting 9/2003
Description: Examines how birth weight and other prenatal and childhood factors influences risk for diabetes, heart disease, breast cancer and brain function in adulthood. This project is collaboration between CHDS investigators and Columbia University (Ezra Susser, Principal Investigator), Harvard University, University of California, Davis, and Kaiser Permanente Division of Research. This project launches a new era of research at the CHDS focused on adult health of CHDS "children", now in their 30's and 40's.
Funding Source:
National Institute on Aging

http://www.nia.nih.gov/

*Does not include most projects directed by outside investigators